Indications & Usage of Brentuximab vedotin Adcetris Injection 50mg vial:

Indications:

• Patients should be advised that Brentuximab vedotin Adcetris injection may cause a peripheral neuropathy. They should be told be contact their healthcare provider if any tingling or numbness of feet, weakness of muscles or hands.
• The patient is advised to contact their healthcare provider if a fever is 100.5°F or greater than this. The other proofs of potential infections are a cough, pain on urination develops, or chills.
• Adcetris may harm fetal, the woman who is receiving Adcetris has to be advised to avoid pregnancy and if a woman is pregnant she has to report immediately to her healthcare provider.
• Dose modification has to be done in two ways.

1. Peripheral Neuropathy: dose should be held if the grade is worsened or new to Grade 2 or 3 and it has to restart when neuropathy improves to baseline or Grade 1 and then it has to be restarted at 12 kg/mg. Adcetris has to be discontinued if it reaches Grade 4.
2. Adcetris dose has to be held if it reaches to Grade 3 or 4 neutropenia till it resolves to lower or to baseline or to Grade 2. G-CSF prophylaxis has to be considered for subsequent cycles in patients who are having Grade 3 or 4 neutropenia in the past cycle. For the patients who are recurrent Grade 4 neutropenia in spite of the use of G-CSF prophylaxis, the dosage has to be considered as discontinuation or dosage has to be reduced to 1.2 mg/kg.

Usage:

• Brentuximab vedotin Adcetris has to be administered until the disease progression or till unacceptable toxicity as an intravenous infusion over 30 minutes in every 3 weeks.
• Brentuximab vedotin Adcetris has to be administered only as an intravenous infusion and it should not be mixed with other medicinal products.
• Do not shake and gently swirl the vial to aid dissolution.
• Each 50 mg vial of Brentuximab vedotin Adcetris injection has to be reconstituted with 10.5 ml of Sterile water for injection, USP. to produce a single-use solution that contains 5 ml/mg of Brentuximab vedotin Adcetris.
• For the number of 50 mg vials has to be decided based on the need of patient’s weight and as per the prescribed dose.
• After reconstitution, the diluted solution has to be immediately into an infusion bad and if it has not diluted then immediately has to be stored at 2-8°C (36-46°F) and this solution has to be used within 24 hours of reconstitution. This solution should not be frozen.
• The unused portion of the vial that is left has to be discarded.

How supplied/ storage and handling?

• Brentuximab vedotin Adcetris has to be stored as vial at 2-8°C (36–46°F) in its original carton to be protected from light.
• Brentuximab vedotin Adcetris has to be specially handled and to be disposed of as per disposal procedure, as it is an antineoplastic product.
• Keep medicine out of reach of children.

Adcetris is supplied as follows:

Adcetris has to be used as the injection is supplied as a sterile, white to off-white preservative-free lyophilized powder or cake in individually boxed for single use vials like 50 mg brentuximab.

Sourcing in India: Ram Health Care exports and imports of licensed products. Ram Health Care provides services in India, Dubai, Hongkong, Asia, Europe, USA, Philippines, and the UK. we provide services that include patient service programs and logistics support for the international clinical trials. Our main vision is to facilitate the solutions with an area by setting benchmark standards.

What is the generic name for the drug Adcetris injection?

Brentuximab is the generic name for Adcetris injection. Injection Adcetris (Brentuximab vedotin) is used in treating patients who are Hodgkin Lymphoma (HL) it happens after the failure of minimum two prior multi-agent chemotherapy regimens in the patients who are not ASCT or after the failure of autologous stem cell transplant (ASCT) prospects. And this injection is also used for the treating patients who are Systemic Anaplastic Large Cell Lymphoma (SALCL) it happens after the failure of minimum one prior multi-agent chemotherapy regimen.

What is the manufacturer name of  Brentuximab vedotin Adcetris injection?

Seattle Genetics, Inc. is the manufacturer name of Brentuximab vedotin Adcetris injection. Adcetris injection is manufactured by Seattle Genetics, Inc. Bothell, WA, Seattle Genetics manufacture the vaccines, medicines, and consumer healthcare products. it is the leading healthcare company in WA.

What is the dosage and form of  Brentuximab vedotin Adcetris?

• Each Brentuximab vedotin Adcetris injection 50 mg vial has to be reconstituted with 10.5 ml of Sterile water for injection, USP. to produce a single-use solution that contains 5 ml/mg of Brentuximab vedotin Adcetris.
• For the number of 50 mg vials has to be decided based on the need of patient’s weight and as per the prescribed dose.

Is Brentuximab vedotin Adcetris injection approved by FDA?

Yes,  Brentuximab vedotin Adcetris injection is available in India. and it is approved by FDA in Initial U.S. approval: 2011

Highlights of Prescribing Information of Brentuximab vedotin Adcetris

• The patient is advised to contact their healthcare provider if a fever is 100.5°F or greater than this. The other proofs of potential infections are a cough, pain on urination develops, or chills.
• Dose modification has to be done in two ways.

1. Peripheral Neuropathy: dose should be held if the grade is worsened or new to Grade 2 or 3 and it has to restart when neuropathy improves to baseline or Grade 1 and then it has to be restarted at 12 kg/mg. Adcetris has to be discontinued if it reaches Grade 4.
2. Brentuximab vedotin Adcetris dose has to be held if it reaches to Grade 3 or 4 neutropenia till it resolves to lower or to baseline or to Grade 2. G-CSF prophylaxis has to be considered for subsequent cycles in patients who are having Grade 3 or 4 neutropenia in the past cycle. For the patients who are recurrent Grade 4 neutropenia in spite of the use of G-CSF prophylaxis, the dosage has to be considered as discontinuation or dosage has to be reduced to 1.2 mg/kg.

• Do not shake and gently swirl the vial to aid dissolution.
• After reconstitution, the diluted solution has to be immediately into an infusion bad and if it has not diluted then immediately has to be stored at 2-8°C (36-46°F) and this solution has to be used within 24 hours of reconstitution. This solution should not be freezed.
• The unused portion of the vial that is left has to be discarded.

Is Brentuximab vedotin Adcetris injection available in India

Brentuximab vedotin Adcetris injection is a pharma drug that legally requires a prescription from the medical practitioner.

Ram Healthcare is able to procure all drugs under named patient program. Importing in minimum time with 100% legal clearance.

All the drug procurement/import with Ram Healthcare is done following the government policies strictly and insuring 100% transparency.

You can contact us for the inputs on

• Availability of Brentuximab vedotin Adcetris injection in India
• Brentuximab vedotin Adcetris injection price in India
• Brentuximab vedotin Adcetris injection availability in Chennai, Bangalore, Hyderabad, Mumbai, Delhi, Ahmedabad and all other major cities in India

What is the price of Brentuximab vedotin Adcetris injection in India

Send your enquiry to find the Cost of Brentuximab vedotin Adcetris injection in India at

Phone No: 8939896944   Email: query@rhcglobal.com

How Brentuximab vedotin Adcetris injection is supplied

Brentuximab vedotin Adcetris injection is supplied as a sterile, white to off-white preservative-free lyophilized powder or cake in individually boxed for single use vials like 50 mg brentuximab.

Where can i buy Brentuximab vedotin Adcetris injection online

Ram Healthcare Pvt Ltd connects buyer with the supplier who can ship Brentuximab vedotin Adcetris injection to any country of the world as per the buyer’s requirement and Government regulations of the country.
Ram Healthcare Pvt Ltd provides options of choosing exporter and supplier of Cancer
treatment Medicines We take guarantee of quality and delivery anywhere in the world as per the buyer’s requirements.

How order Brentuximab vedotin Adcetris injection online will be confirmed?

The order will be confirmed only after the receipt of Valid prescription of Clinician

Disclaimer:

Please note that all information in relation to this drug is of general nature and may not be applicable to your specific situation and circumstance. Any information available here is not a substitute for professional medical advice by a licensed practitioner. We will help you in importing this medicine only upon the valid prescription of a licensed medical practitioner and other documents as required by the laws of the jurisdiction in which you are present.