Zelboraf (Vemurafenib) Tablets 240 mg


Facts of Zelboraf (Vemurafenib) Tablets 240 mg ?

  • Medicine Name: ZELBORAF
  • Generic Name: VEMURAFENIB
  • Date of Approval: 17.08.2011
  • Company Name: ROCHE.

What is Zelboraf ?

ZELBORAF (vemurafenib) is a kinase inhibitor available as 240 mg tablets for oral use. Vemurafenib has the chemical name propane-1-sulfonic acid {3-[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4 difluoro-phenyl}-amide. It has the molecular formula C23H18ClF2N3O3S and a molecular weight of 489.9

What are the indications and usage?

ZELBORAF™ is a kinase inhibitor indicated for the treatment of patients with unresectable or metastatic melanoma with BRAFV600E mutation as detected by an FDA-approved test

Limitation of Use: ZELBORAF is not recommended for use in patients with wild-type BRAF melanoma

How supplied/storage and handling ?

ZELBORAF (vemurafenib) is supplied as 240 mg film-coated tablets with VEM debossed on one side in single bottle of 120 count. The following packaging configuration is available:

  • Storage and Stability: Store at room temperature 20°C – 25°C (68°F – 77°F); excursions permitted between 15°C and 30°C (59°F and 86°F), See USP Controlled Room Temperature. Store in the original container with the lid tightly closed.
  • Disposal of unused/expired medicines: The release of pharmaceuticals in the environment should be minimized. Medicines should not be disposed of via wastewater and disposal through household waste should be avoided. Use established “collection systems”, if available in your location.